DOTA-Lanreotide: A Novel Somatostatin Analog for Tumor Diagnosis and Therapy1

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Novel DOTA- -Melanocyte–Stimulating Hormone Analog for Metastatic Melanoma Diagnosis

Scintigraphic imaging of metastatic melanoma lesions requires highly tumor-specific radiolabeled compounds. Because both melanotic and amelanotic melanomas overexpress receptors for -melanocyte–stimulating hormone ( -MSH; receptor name: melanocortin type 1 receptor, or MC1R), radiolabeled -MSH analogs are potential candidates for melanoma diagnosis. The aim of this study was to develop a melano...

متن کامل

A Novel Fuzzy-C Means Image Segmentation Model for MRI Brain Tumor Diagnosis

Accurate segmentation of brain tumor plays a key role in the diagnosis of brain tumor. Preset and precise diagnosis of Magnetic Resonance Imaging (MRI) brain tumor is enormously significant for medical analysis. During the last years many methods have been proposed. In this research, a novel fuzzy approach has been proposed to classify a given MRI brain image as normal or cancer label and the i...

متن کامل

A novel lanreotide-encoded micelle system targets paclitaxel to the tumors with overexpression of somatostatin receptors.

Many tumor cells specifically overexpress somatostatin receptors, in particular, subtype 2 (SSTR2). Lanreotide, a somatostatin analogue with high affinity for SSTR2, can be exploited as a ligand for tumor targeted therapy. In this study, lanreotide was first conjugated to poly(ethylene glycol)-b-poly(ε-caprolactone) (PEG-b-PCL) copolymer, and the active targeting micelles with paclitaxel (lanre...

متن کامل

Somatostatin Receptors in the Diagnosis and Therapy of Neuroendocrine Tumor.

The expression of somatostatin receptors in neuroendocrine tumors has facilitated the diagnosis and surgical treatment of patients with these tumors. After injection of a radiolabeled long-acting somatostatin analog, (111)In-octreotide, scintigraphic tumor imaging can ben performed as well as intraoperative tumor localization. During localization studies very high (111)In concentration values w...

متن کامل

NASBA Isothermal Technique: a Novel Tool for Mycobacterium tuberculosis Diagnosis

Background and Objectives: rapid, accurate and cost effective diagnosis of infectious and non infectious diseases is an essential step for treatment process. Nowadays, in Line with scientific progression in molecular biology, genetics and biochemistry which are based on biotechnology and genetic engineering aspects, new branch of medicine entitled molecular medicine is being derived. It can be ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Endocrinology

سال: 1999

ISSN: 0013-7227,1945-7170

DOI: 10.1210/endo.140.11.7126